Publications

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Sobol M, Nebesářová J, Hozák P. (2011)
A method for preserving ultrastructural properties of mitotic cells for subsequent immunogold labeling using low-temperature embedding in LR White resin
Histochem Cell Biol. 135,103-10
abstract

Sobol M, Philimonenko VV, Hozák P.(2010)
Comparison of methods of high-pressure freezing and automated freeze-substitution of suspension cells combined with LR White embedding
Histochem Cell Biol. 134, 631-41
abstract

  Philimonenko AA, Janacek J, Snyers L, Almeder M, Berger W, Schmidt W, Schöfer C, Hozák P, Weipoltshammer K. (2010)
Chromosomal dynamics of cell cycle regulator gene p21 during transcriptional activation.
J Struct Biol. 173, 382-90
abstract
Philimonenko VV, Janácek J, Harata M, Hozák P.  (2010)
Transcription-dependent rearrangements of actin and nuclear myosin I in the nucleolus.
Histochem Cell Biol., 134, 243-9
abstract

Castano E, Philimonenko VV, Kahle M, Fukalová J, Kalendová A, Yildirim S, Dzijak R, Dingová-Krásna H, Hozák P.  (2010)
Actin complexes in the cell nucleus: new stones in an old field.
Histochem Cell Biol., 133, 607-26
abstract

Novakova Z, Hubackova S, Kosar M, Janderova-Rossmeislova L, Dobrovolna J, Vasicova P, Vancurova M, Horejsi Z, Hozak P, Bartek J, Hodny Z.  (2010)
Cytokine expression and signaling in drug-induced cellular senescence.
Oncogene, 29, 273-84
abstract

Dingová H., Fukalová J., Maninová M., Philimonenko V.V., Hozák P. (2008)
Ultrastructural localization of actin and actin-binding proteins in the nucleus.
Histochem Cell Biol., 131, 425 - 34
abstract

Ogushi S, Palmieri CH, Fulka H, Saitou M, Myiano T, Fulka J Jr. (2008)
The maternal nucleolus is essential for early embryonic development in mammals.
Science, 319, 613-16 (H. Fulka - past PhD student in the lab)
abstract

Fulka H., Barnetová I, Moško T., Fulka J. (2008)
Epigenetic analysis of human spermatozoa after their injection into ovulated mouse oocytes.
Human Reproduction, 23, 627-34
(H. Fulka - past PhD student in the lab)
abstract

Fulka H. (2008)
Changes in global histone acetylation pattern in somatic cell nuclei after their transfer into oocytes at different stages of maturation.
Mol Reprod Dev, 75, 556-64
(H. Fulka - past PhD student in the lab)
abstract

Stradalova V., Gaplovska-Kysela K., Hozak P. (2008)
Ultrastructural and nuclear antigen preservation after high-pressure freezing/freeze-substitution and low-temperature LR White embedding of HeLa cells.

Histochem Cell Biol, 130, 1047-52
abstract

Fulka H, St John JC,  Fulka J, Hozak P. (2008)
Chromatin in early mammalian embryos: achieving the pluripotent state.
Differentiation, 76, 3-14
abstract

Janderova-Rossmeislova L., Novakova Z., Vlasakova J., Philimonenko V., Hozak  P., Hodny Z. (2007)
PML protein association with specific nucleolar structures differs in normal, tumor and senescent human cells.
J Struct Biol, 159, 56-70
abstract 

Hrebicek M., Jirasek T., Hartmannova H., Noskova L., Stranecky V., Ivanek R., Kmoch S., Cebecauerova D., Vitek L., Mikulecky M., Subhanova I., Hozak P., Jirsa M. (2007)
Rotor-type hyperbilirubinaemia has no defect in the canalicular bilirubin export pump.
Liver Int, 27, 485-91
abstract

Vlasakova J., Novakova Z., Rossmeislova L., Kahle M., Hozak P., Hodny Z. (2007) Histone deacetylase inhibitors suppress IFNalpha-induced up-regulation of promyelocytic leukemia protein.
Blood, 109, 1373-80
abstract

Kahle M., Pridalova J., Spacek M., DzijakR. and Hozak P. (2006)
Nuclear myosin is ubiquitously expressed and evolutionary conserved in vertebrates.
Histochem Cell Biol, in press

Philimonenko A., Hodny Z., Jackson D.A. and Hozak P. (2006)
The microarchitecture of DNA replication domains.
Histochem Cell Biol, 125, 103-117
abstract

Novakova Z., Man P., Novak P., Hozak P., Hodny Z. (2006)
Separation of nuclear protein complexes by blue native polyacrylamide gel electrophoresis.
Electrophoresis, 27, 1-11
abstract

  Hozak P., Fakan S. (2006)
Functional structure of the cell nucleus.
Histochem Cell Biol., 125, 1-2
abstract

Baran V., Kovarova H., Klima J., Hozak P., Motlik J. (2006)
Re-localization of nuclear DNA helicase II during the growth period of bovine oocytes.
Histochem Cell Biol., 125, 155-164
abstract

Pokorna D., Cerovska N., Smahel M., Moravec T., Ludvikova V., Mackova J., Synkova H., Duskova M., Hozak P., Veleminsky J. (2005)
DNA vaccines based on chimeric potyvirus - like particles carrying HPV16 E7 peptide (aa 44-60).
Oncol. Rep.,
14, 1045-1053
abstract

Peknicova J., Chladek D., Hozak P. (2005)
Monoclonal antibodies against sperm intra-acrosomal antigens as markers for male infertility diagnostics and estimation of spermatogenesis.
Am. J. Reprod. Immunol., 53, 42-49
abstract

Libusova L., Sulimenko T., Sulimenko V., Janisch R., Hozak P., Draber P. (2005)
Distinct localization of a beta-tubulin epitope in the Tetrahymena thermophila and Paramecium caudatum cortex.
Protoplasma, 225, 157-167
abstract

Kysela K., Philimonenko A., Philimonenko V., Janacek J., Kahle M., Hozak P. (2005) Nuclear distribution of actin and myosin I depends on transcriptional activity of the cell.
Histochem Cell Biol., 124, 347-358
abstract

Feltl D., Zavadova E., Pala M., Hozak P. (2005)
Post-treatment plasma transforming growth factor beta 1 (TGF-beta 1) level predicts for late morbidity in patients with advanced head and neck cancer.
Neoplasma, 52, 393-397
abstract

Feltl D., Zavadova E., Pala M., Hozak P. (2005)
The dynamics of plasma transforming growth factor beta 1 (TGF-beta1) level during radiotherapy with or without simultaneous chemotherapy in advanced head and neck cancer.
Oral. Oncol., 41, 208-213
abstract

Cebacauer M., Guillaume P., Hozak P., Mark S., Everett H., Schneider P. and Luescher I. F. (2005)
Solutable MHC-Peptide Complexes Induce Rapid Death CD8+ CTL1.
The Journal of Imunology, 174, 6809-6819
abstract

Schoefer Ch., Janacek J., Weipoltshammer K., Pourani J. and Hozak P. (2004)
Mapping of cellular compartments based on ultrastructural immunogold labeling.
Jurnal of Structural Biology, 147, 128-135
abstract

Philimonenko A., Jackson D.A., Hodny Z., Janacek J., Cook P.R. and Hozak P. (2004)
Dynamics of DNA replication: an ultrastructural study.
Jurnal of Structural Biology, 148, 279-289
abstract

Philimonenko V., Zhao J., Iben S., Dingova H., Kysela K., Kahle M., Zentgraf H., Hofmann W.A., de Lamerolle P., Hozak P. and Grummt I. (2004)
Nuclear actin and myosine I are required for RNA polymerase I transcription.
Nature Cell Biology, 12, 1165-1172
abstract

Mullerova J., Hozak P. (2004)
Use of recombinant congenic strains in mapping disease-modifying genes.
News Physiol Sci.,
19, 105-109
abstract

Hofmann W., Stojiljkovic L., Fuchsova B., Vargas G. M., Mavrommatis E., Philimonenko V., Kysela K., Goodrich J.A., Lessard J.L., Hope T.J., Hozak P and de Lamerolle P. (2004)
Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II.
Nature Cell Biology, 11, 1094-1101
abstract

Degrouard J., Hozak P., Heyman Y., Flechon J.-E. (2004)
Nucleoskeleton of early bovine embryos and differentiated somatic cells: an ultrastructural and immunocytochemical comparison.
Histochem Cell Biol, 121, 441-451
abstract

Chovanec M., Smetana Jr K., Purkrabkova T.,Holikova Z., Dvorankova B., Andre S., Pytlik R., Hozak P., Plzak J., Sedo A., Vacik J., Gabius H. (2004)
Detection of cell type and marker specificity of nuclear binding sites for anionic carbohydrate ligands.
Biotech Histochem., 79, 139-150

Bjerregaard B., Wrenzycki Ch., Philimonenko V., Hozak P., Laurincik J., Niemann H., Motlik J. and Maddox-Hyttel P. (2004)
Regulation of ribosomal RNA synthesis during the final phases of porcine oocyte growth.
Biology of reproduction, 70, 925-935
abstract

Baran V., Pavlok A., Bjerregaard B., Wrenzycki Ch., Hermann D., Philimonenko V., Lapathitis G., Hozak P., Niemann H., Motlik J. (2004)
Immunolocalization of Upstream Binding Factor and Pocket Protein p130 During Final Stages of Bovine Oocyte Growth.
Biol. of Reproduction, 70, 877-886
abstract

Libusova L., Sulimenko T., Sulimenko V., Hozak P., Draber P.. (2004)
Gamma-Tubulin in Leishmania: cell cycle-dependent changes in subcellular localization and heterogeneity of its isoforms.
Experimental Cell Research, 125, 375-386
abstract

Kuchaschova S., Filimonenko V., Gulak P., Kireev I., Poliakov V., Hozak P. (2003)
Induction of nuclear envelope formation around individual chromosomes under impact of hypotonic shock.
Tsitologiia, 45, 298-307
abstract

Jirásek T., Hozák P. and Mandys V. (2003)
Different patterns of chromogranin A and Leu-7 (CD57) expression in gastrointestinal carcinoids: immunohistochemical and confocal laser scanning microscopy study.
Neoplasma, 50,
abstract

Fuchsová B. and Hozák P. (2002)
The localization of nuclear DNA helicase II in diferent nuclear compartment is linked to transcription.
Exp. Cell Res., 279, 260-70 

abstract

Fuchsova B., Novak P., Kafkova J. and Hozak P. (2002)
Nuclear DNA helicase II is recruited to IFN-alpha activated transcription sites at PML nuclear bodies.
J. Cell Biol., 158, 463-473
abstract

Philimonenko V.V., Janacek J. and Hozak P. (2002)
LR White is preferable to Unicryl for immunogold detection of fixation-sensitive nuclear antigens.
Eur. J. Histochem., 46, 359-364

Iben S., Tschochner H., Bier M., Hozak P., Egly J.-M. and Grummt I. (2002)
TFIIH plays a role in RNA polymerase I transcription.
Cell, 109, 297-306
abstract

Sutovsky P., Motlik J., ... Hozak P., … Zudova D. (2001)
Accumulation of the proteolytic marker Peptide ubiquitin in the trophoblast of Mammalian blastocysts.
Cloning Stem Cells, 3, 157-161

Mosgoeller W., Schoefer Ch., Steiner M., Sylvester J.E. and Hozák P. (2001) Arrangement of active ribosomal genes in nucleolar domains revealed by detection of "christmas trees" in situ.
Histochem. Cell Biol., 116, 495-505

Richterová Z., Liebl D., Horák M., Palková Z., Štokrová J., Hozák P., Korb J. and Forstová J. (2001)
Caveolae are involved in the trafficking of mouse polyomavirus virions and artificial VP1 pseudocapsids toward cell nuclei.
J. Virol., 75, 10880-91
abstract

Philimonenko A.A., Janácek J. and Hozák P. (2001)
Statistical evaluation of clustering and co-localization patterns.
Biotech International, 13, 20-24

Peknicová J., Kubátová A., Sulimenko V., Dráberová E., Viklický V., Hozák P. and Dráber P. (2001)
Differential subcellular distribution of tubulin epitopes in boar spermatozoa. Recognition of class III beta-tubulin epitope in sperm tail.
Biol. Reprod., 65, 672-679
abstract

Philimonenko V.V., Flechon J.-E. and Hozák P. (2001)
The nucleoskeleton: a permanent structure of cell nuclei regardless of their transcriptional activity.
Exp. Cell Res., 264, 201-210
abstract

Philimonenko A.A., Janacek J. and Hozak P. (2000)
Statistical analysis of colocalization patterns in immunogold labelling experiments. J. Struct. Biol., 132, 201-210

abstract

Pestic-Dragovich L., Stojiljkovic L.,. Philimonenko A.A, Nowak G., Yunbo Ke, Settlage R.E., Shabanowitz J., Hunt D. F. , Hozák P. and de Lanerolle P. (2000)
A myosin I isoform in the nucleus.
Science, 290, 337-341.
abstract

Weipoltshammer K., Schöfer Ch., Almeder M., Philimonenko V.V., Frei K., Wachtler F. and Hozák P. (1999)
Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA.
J. Cell Biol., 147, 1409-1418
abstract

Smetana K., Jiraskova L., Sedlackova M., Dvorak R., Spatova M. and Hozak P. (1998)
Preferential silver reaction of nucleolar regions adjacent
to fibrillar centers in ring shaped nucleoli of leukemic lymphocytes.
Acta Histochem., 100, 257-270
abstract

Moos J., Peknicova J., Geussova G., Philimonenko V.V. and Hozak P. (1998) Association of protein kinase A type I with the sperm cytoskeleton.
Mol. Reprod. Dev., 50, 79-85
abstract

Geussova G., Peknicova J., Capkova J., Kalab P., Moos J., PhilimonenkoV.V. and  Hozak P. (1997)
Monoclonal antibodies to intraacrosomal dog sperm proteins recognizing acrosomal status during capacitaion and acrosome reaction.
Andrologia, 29, 261-268
abstract

Nowak G., Pestic-Dragovich L., Hozak P., Philimonenko A., Simerly C., Schatten G. and de Lanerolle P. (1997)
Evidence for the presence of myosin I in the nucleus.
J.Biol. Chem., 272, 17176-17181

abstract

Hozak P. (1996)
The nucleoskeleton and attached activities.
Exp. Cell Res., 229, 267-271
abstract

Weipoltshammer K., Schofer Ch., Wachtler F. and Hozak P. (1996)
The transcription unit of ribosomal genes is attached to the nuclear skeleton.
Exp. Cell Res., 227, 374-379
abstract

Mosgoeller W., Steiner M., Hozak P., Penner E. and Wesierska-Gadek J. (1996) Nuclear architecture and ultrastructural distribution of poly (ADP-ribosyl) transferase, a multifunctional enzyme.
J. Cell Sci., 109, 409-418
abstract

Hozak P., Jackson D.A. and Cook P.R. (1996)
Role of nuclear structure in DNA replication. In: Eukaryotic DNA Replication - Frontiers in Molecular Biology.
J.J. Blow, Ed., Oxford University Press, Oxford, Chapter 5, 124-142

Kanka J., Hozak P., Heyman Y., Chesne P., Renard J.-P. and Flechon J.E. (1996) Transcriptional activity and nucleolar ultrastructure of embryonic rabbit nuclei after transplantation to enucleated oocytes.
Mol. Reprod. Dev., 43, 135-144
abstract

Hughes T.A., Pombo A., McManus J., Hozak P., Jackson D.A. and Cook P.R. (1995)
On the structure of replication and transcription factories.
J. Cell Sci., Supp. 19, 59-65
abstract

Hozak P. (1995)
Catching RNA polymerase I in flagranti: rRNA is transcribed in the dense fibrillar component of the nucleolus.
Exp. Cell Res., 216, 285-289
abstract

Hozak P., Sasseville A. M.-J., Raymond Y. and Cook P.R. (1995)
Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells.
J. Cell Sci., 108, 635-644

abstract

Hozak P., Jackson D.A. and Cook P.R. (1994)
Replication factories and nuclear bodies: the ultrastructural characterization of replication sites during the cell cycle.
J. Cell Sci., 107, 2191-2202.
abstract

Hozak P. and Cook P.R. (1994)
Replication factories.
Trends Cell Biol., 4, 48-51.
abstract

Hozak P., Cook P.R., Schoefer Ch., Mosgoeller W. an and Wachtler F. (1994)
Site of transcription of ribosomal RNA and intranucleolar structure in HeLa cells.
J. Cell Sci., 107, 639-648
abstract

Wachtler F., Mosgeoller W., Schoefer C., Sylvester J., Hozak P., Derenzini M. and Stahl A. (1993)
Ribosomal genes and nucleolar morphology.
Chromosomes Today, 11, 63-77

Hozak P., Schoefer C., Sylvester J. and Wachtler F. (1993)
Study on DNA distribution in nucleoli: Isolation of DNA from fibrillar components and ultrastructural localization of different DNA probes.
J. Cell Sci., 104, 1199-1205

abstract

Hozak P., Hassan A.B., Jackson D.A. and Cook P.R. (1993)
Visualisation of replication factories attached to a nucleoskeleton.
Cell, 73, 361-374
abstract

Cook P.R., Dolle A., Hassan A.B. Hozak P., Jackson D.A. (1993)
The role of the nucleoskeleton in RNA metabolism.
Nucleic Acids and molecular biologyl, 7, 226-237

Behalova B., Hozak P., Blahova M. and Sillinger V. (1992)
Effect of nitrogen limitation and sporulation on sterol and lipid formation in Saccharomyces cerevisiae.
Folia Microbiol., 37, 442-449

abstract

Hozak P., Geraud G. and Hernandez-Verdun D. (1992)
Revealing nucleolar architecture by low ionic strength treatment.
Exp. Cell Res., 203, 128-133

abstract

Hozak P., Roussel P. and Hernandez-Verdun D. (1992)
Procedures for specific detection of silver stained nucleolar proteins on Western blots.
J. Histoch. Cytoch., 40, 1089-1096
abstract

Hozak P., Zatsepina O.V. and Likovsky Z. (1990)
Nucleolar changes in hypotonic treatment and the possibility of isolation of nucleolar fibrillar complexes.
Nuclear Structure and function, Harris J.R. and Zbarsky I.B. Eds, Plenum Press, new York, 197-202

Hozak P., Zatsepina O.V. and Likovsky Z. (1990)
In situ separation of nucleolar components by hypotonic treatment of cells.
Biol. Cell, 68, 167-170
abstract

Hozak P., Novak J., Smetana K. (1989)
Three-dimensional reconstructions of nucleous organizing regions in PHA - stimulated human lymphocytes.
Biol. Cell, 66, 225-233
abstract

Zatsepina O., Hozak P., Babadjanyan D., Chensov I. (1988)
Morphometric study of nucleolus-organizing regions of chromosomes from swine embryo kidney cells during Go-, G2-period and mitosis.
Mol Biol., 22, 1015-1025
abstract

Zatsepina O.V., Hozak P., Babadjanyan D. and Chensov Yu.S. (1988)
Quantitative ultrastructural study of nucleous-organizing regions at some stages of the cell cycle (Go period, G2 period, mitosis).
BIol. Cell., 62, 211-218
abstract

Hozak P., Zatsepina O.V., Vasilyeva I. and Chensov Yu.S. (1986)
An electron microscopic study of nucleous-organizing regions at some stages of the cell cycle (Go period, G2 period, mitosis).
BIol. Cell., 57, 197-206
abstract

Hozak P., Zatsepina O.V. and Chensov Yu.S. (1983)
Ultrastructure, shape and number of fibrillar centers in PK-cells begin Go.
Citologia, 25, 1236-1242