Intellectual Property Rights

Sobol M, Nebesářová J, Hozák P. (2011)
A method for preserving ultrastructural properties of mitotic cells for subsequent immunogold labeling using low-temperature embedding in LR White resin
Histochem Cell Biol. 135,103-10

Sobol M, Philimonenko VV, Hozák P.(2010)
Comparison of methods of high-pressure freezing and automated freeze-substitution of suspension cells combined with LR White embedding
Histochem Cell Biol. 134, 631-41

  Philimonenko AA, Janacek J, Snyers L, Almeder M, Berger W, Schmidt W, Schöfer C, Hozák P, Weipoltshammer K. (2010)
Chromosomal dynamics of cell cycle regulator gene p21 during transcriptional activation.
J Struct Biol. 173, 382-90
Philimonenko VV, Janácek J, Harata M, Hozák P.  (2010)
Transcription-dependent rearrangements of actin and nuclear myosin I in the nucleolus.
Histochem Cell Biol., 134, 243-9

Castano E, Philimonenko VV, Kahle M, Fukalová J, Kalendová A, Yildirim S, Dzijak R, Dingová-Krásna H, Hozák P.  (2010)
Actin complexes in the cell nucleus: new stones in an old field.
Histochem Cell Biol., 133, 607-26

Novakova Z, Hubackova S, Kosar M, Janderova-Rossmeislova L, Dobrovolna J, Vasicova P, Vancurova M, Horejsi Z, Hozak P, Bartek J, Hodny Z.  (2010)
Cytokine expression and signaling in drug-induced cellular senescence.
Oncogene, 29, 273-84

Dingová H., Fukalová J., Maninová M., Philimonenko V.V., Hozák P. (2008)
Ultrastructural localization of actin and actin-binding proteins in the nucleus.
Histochem Cell Biol., 131, 425 - 34

Ogushi S, Palmieri CH, Fulka H, Saitou M, Myiano T, Fulka J Jr. (2008)
The maternal nucleolus is essential for early embryonic development in mammals.
Science, 319, 613-16 (H. Fulka - past PhD student in the lab)

Fulka H., Barnetová I, Moško T., Fulka J. (2008)
Epigenetic analysis of human spermatozoa after their injection into ovulated mouse oocytes.
Human Reproduction, 23, 627-34
(H. Fulka - past PhD student in the lab)

Fulka H. (2008)
Changes in global histone acetylation pattern in somatic cell nuclei after their transfer into oocytes at different stages of maturation.
Mol Reprod Dev, 75, 556-64
(H. Fulka - past PhD student in the lab)

Stradalova V., Gaplovska-Kysela K., Hozak P. (2008)
Ultrastructural and nuclear antigen preservation after high-pressure freezing/freeze-substitution and low-temperature LR White embedding of HeLa cells.

Histochem Cell Biol, 130, 1047-52

Fulka H, St John JC,  Fulka J, Hozak P. (2008)
Chromatin in early mammalian embryos: achieving the pluripotent state.
Differentiation, 76, 3-14

Janderova-Rossmeislova L., Novakova Z., Vlasakova J., Philimonenko V., Hozak  P., Hodny Z. (2007)
PML protein association with specific nucleolar structures differs in normal, tumor and senescent human cells.
J Struct Biol, 159, 56-70

Hrebicek M., Jirasek T., Hartmannova H., Noskova L., Stranecky V., Ivanek R., Kmoch S., Cebecauerova D., Vitek L., Mikulecky M., Subhanova I., Hozak P., Jirsa M. (2007)
Rotor-type hyperbilirubinaemia has no defect in the canalicular bilirubin export pump.
Liver Int, 27, 485-91

Vlasakova J., Novakova Z., Rossmeislova L., Kahle M., Hozak P., Hodny Z. (2007) Histone deacetylase inhibitors suppress IFNalpha-induced up-regulation of promyelocytic leukemia protein.
Blood, 109, 1373-80

Kahle M., Pridalova J., Spacek M., DzijakR. and Hozak P. (2006)
Nuclear myosin is ubiquitously expressed and evolutionary conserved in vertebrates.
Histochem Cell Biol, in press

Philimonenko A., Hodny Z., Jackson D.A. and Hozak P. (2006)
The microarchitecture of DNA replication domains.
Histochem Cell Biol, 125, 103-117

Novakova Z., Man P., Novak P., Hozak P., Hodny Z. (2006)
Separation of nuclear protein complexes by blue native polyacrylamide gel electrophoresis.
Electrophoresis, 27, 1-11

  Hozak P., Fakan S. (2006)
Functional structure of the cell nucleus.
Histochem Cell Biol., 125, 1-2

Baran V., Kovarova H., Klima J., Hozak P., Motlik J. (2006)
Re-localization of nuclear DNA helicase II during the growth period of bovine oocytes.
Histochem Cell Biol., 125, 155-164

Pokorna D., Cerovska N., Smahel M., Moravec T., Ludvikova V., Mackova J., Synkova H., Duskova M., Hozak P., Veleminsky J. (2005)
DNA vaccines based on chimeric potyvirus - like particles carrying HPV16 E7 peptide (aa 44-60).
Oncol. Rep.,
14, 1045-1053

Peknicova J., Chladek D., Hozak P. (2005)
Monoclonal antibodies against sperm intra-acrosomal antigens as markers for male infertility diagnostics and estimation of spermatogenesis.
Am. J. Reprod. Immunol., 53, 42-49

Libusova L., Sulimenko T., Sulimenko V., Janisch R., Hozak P., Draber P. (2005)
Distinct localization of a beta-tubulin epitope in the Tetrahymena thermophila and Paramecium caudatum cortex.
Protoplasma, 225, 157-167

Kysela K., Philimonenko A., Philimonenko V., Janacek J., Kahle M., Hozak P. (2005) Nuclear distribution of actin and myosin I depends on transcriptional activity of the cell.
Histochem Cell Biol., 124, 347-358

Feltl D., Zavadova E., Pala M., Hozak P. (2005)
Post-treatment plasma transforming growth factor beta 1 (TGF-beta 1) level predicts for late morbidity in patients with advanced head and neck cancer.
Neoplasma, 52, 393-397

Feltl D., Zavadova E., Pala M., Hozak P. (2005)
The dynamics of plasma transforming growth factor beta 1 (TGF-beta1) level during radiotherapy with or without simultaneous chemotherapy in advanced head and neck cancer.
Oral. Oncol., 41, 208-213

Cebacauer M., Guillaume P., Hozak P., Mark S., Everett H., Schneider P. and Luescher I. F. (2005)
Solutable MHC-Peptide Complexes Induce Rapid Death CD8+ CTL1.
The Journal of Imunology, 174, 6809-6819

Schoefer Ch., Janacek J., Weipoltshammer K., Pourani J. and Hozak P. (2004)
Mapping of cellular compartments based on ultrastructural immunogold labeling.
Jurnal of Structural Biology, 147, 128-135

Philimonenko A., Jackson D.A., Hodny Z., Janacek J., Cook P.R. and Hozak P. (2004)
Dynamics of DNA replication: an ultrastructural study.
Jurnal of Structural Biology, 148, 279-289

Philimonenko V., Zhao J., Iben S., Dingova H., Kysela K., Kahle M., Zentgraf H., Hofmann W.A., de Lamerolle P., Hozak P. and Grummt I. (2004)
Nuclear actin and myosine I are required for RNA polymerase I transcription.
Nature Cell Biology, 12, 1165-1172

Mullerova J., Hozak P. (2004)
Use of recombinant congenic strains in mapping disease-modifying genes.
News Physiol Sci.,
19, 105-109

Hofmann W., Stojiljkovic L., Fuchsova B., Vargas G. M., Mavrommatis E., Philimonenko V., Kysela K., Goodrich J.A., Lessard J.L., Hope T.J., Hozak P and de Lamerolle P. (2004)
Actin is part of pre-initiation complexes and is necessary for transcription by RNA polymerase II.
Nature Cell Biology, 11, 1094-1101

Degrouard J., Hozak P., Heyman Y., Flechon J.-E. (2004)
Nucleoskeleton of early bovine embryos and differentiated somatic cells: an ultrastructural and immunocytochemical comparison.
Histochem Cell Biol, 121, 441-451

Chovanec M., Smetana Jr K., Purkrabkova T.,Holikova Z., Dvorankova B., Andre S., Pytlik R., Hozak P., Plzak J., Sedo A., Vacik J., Gabius H. (2004)
Detection of cell type and marker specificity of nuclear binding sites for anionic carbohydrate ligands.
Biotech Histochem., 79, 139-150

Bjerregaard B., Wrenzycki Ch., Philimonenko V., Hozak P., Laurincik J., Niemann H., Motlik J. and Maddox-Hyttel P. (2004)
Regulation of ribosomal RNA synthesis during the final phases of porcine oocyte growth.
Biology of reproduction, 70, 925-935

Baran V., Pavlok A., Bjerregaard B., Wrenzycki Ch., Hermann D., Philimonenko V., Lapathitis G., Hozak P., Niemann H., Motlik J. (2004)
Immunolocalization of Upstream Binding Factor and Pocket Protein p130 During Final Stages of Bovine Oocyte Growth.
Biol. of Reproduction, 70, 877-886

Libusova L., Sulimenko T., Sulimenko V., Hozak P., Draber P.. (2004)
Gamma-Tubulin in Leishmania: cell cycle-dependent changes in subcellular localization and heterogeneity of its isoforms.
Experimental Cell Research, 125, 375-386

Kuchaschova S., Filimonenko V., Gulak P., Kireev I., Poliakov V., Hozak P. (2003)
Induction of nuclear envelope formation around individual chromosomes under impact of hypotonic shock.
Tsitologiia, 45, 298-307

Jirásek T., Hozák P. and Mandys V. (2003)
Different patterns of chromogranin A and Leu-7 (CD57) expression in gastrointestinal carcinoids: immunohistochemical and confocal laser scanning microscopy study.
Neoplasma, 50,

Fuchsová B. and Hozák P. (2002)
The localization of nuclear DNA helicase II in diferent nuclear compartment is linked to transcription.
Exp. Cell Res., 279, 260-70 


Fuchsova B., Novak P., Kafkova J. and Hozak P. (2002)
Nuclear DNA helicase II is recruited to IFN-alpha activated transcription sites at PML nuclear bodies.
J. Cell Biol., 158, 463-473

Philimonenko V.V., Janacek J. and Hozak P. (2002)
LR White is preferable to Unicryl for immunogold detection of fixation-sensitive nuclear antigens.
Eur. J. Histochem., 46, 359-364

Iben S., Tschochner H., Bier M., Hozak P., Egly J.-M. and Grummt I. (2002)
TFIIH plays a role in RNA polymerase I transcription.
Cell, 109, 297-306

Sutovsky P., Motlik J., ... Hozak P., … Zudova D. (2001)
Accumulation of the proteolytic marker Peptide ubiquitin in the trophoblast of Mammalian blastocysts.
Cloning Stem Cells, 3, 157-161

Mosgoeller W., Schoefer Ch., Steiner M., Sylvester J.E. and Hozák P. (2001) Arrangement of active ribosomal genes in nucleolar domains revealed by detection of "christmas trees" in situ.
Histochem. Cell Biol., 116, 495-505

Richterová Z., Liebl D., Horák M., Palková Z., Štokrová J., Hozák P., Korb J. and Forstová J. (2001)
Caveolae are involved in the trafficking of mouse polyomavirus virions and artificial VP1 pseudocapsids toward cell nuclei.
J. Virol., 75, 10880-91

Philimonenko A.A., Janácek J. and Hozák P. (2001)
Statistical evaluation of clustering and co-localization patterns.
Biotech International, 13, 20-24

Peknicová J., Kubátová A., Sulimenko V., Dráberová E., Viklický V., Hozák P. and Dráber P. (2001)
Differential subcellular distribution of tubulin epitopes in boar spermatozoa. Recognition of class III beta-tubulin epitope in sperm tail.
Biol. Reprod., 65, 672-679

Philimonenko V.V., Flechon J.-E. and Hozák P. (2001)
The nucleoskeleton: a permanent structure of cell nuclei regardless of their transcriptional activity.
Exp. Cell Res., 264, 201-210

Philimonenko A.A., Janacek J. and Hozak P. (2000)
Statistical analysis of colocalization patterns in immunogold labelling experiments. J. Struct. Biol., 132, 201-210


Pestic-Dragovich L., Stojiljkovic L.,. Philimonenko A.A, Nowak G., Yunbo Ke, Settlage R.E., Shabanowitz J., Hunt D. F. , Hozák P. and de Lanerolle P. (2000)
A myosin I isoform in the nucleus.
Science, 290, 337-341.

Weipoltshammer K., Schöfer Ch., Almeder M., Philimonenko V.V., Frei K., Wachtler F. and Hozák P. (1999)
Intranuclear anchoring of repetitive DNA sequences: centromeres, telomeres, and ribosomal DNA.
J. Cell Biol., 147, 1409-1418

Smetana K., Jiraskova L., Sedlackova M., Dvorak R., Spatova M. and Hozak P. (1998)
Preferential silver reaction of nucleolar regions adjacent
to fibrillar centers in ring shaped nucleoli of leukemic lymphocytes.
Acta Histochem., 100, 257-270

Moos J., Peknicova J., Geussova G., Philimonenko V.V. and Hozak P. (1998) Association of protein kinase A type I with the sperm cytoskeleton.
Mol. Reprod. Dev., 50, 79-85

Geussova G., Peknicova J., Capkova J., Kalab P., Moos J., PhilimonenkoV.V. and  Hozak P. (1997)
Monoclonal antibodies to intraacrosomal dog sperm proteins recognizing acrosomal status during capacitaion and acrosome reaction.
Andrologia, 29, 261-268

Nowak G., Pestic-Dragovich L., Hozak P., Philimonenko A., Simerly C., Schatten G. and de Lanerolle P. (1997)
Evidence for the presence of myosin I in the nucleus.
J.Biol. Chem., 272, 17176-17181


Hozak P. (1996)
The nucleoskeleton and attached activities.
Exp. Cell Res., 229, 267-271

Weipoltshammer K., Schofer Ch., Wachtler F. and Hozak P. (1996)
The transcription unit of ribosomal genes is attached to the nuclear skeleton.
Exp. Cell Res., 227, 374-379

Mosgoeller W., Steiner M., Hozak P., Penner E. and Wesierska-Gadek J. (1996) Nuclear architecture and ultrastructural distribution of poly (ADP-ribosyl) transferase, a multifunctional enzyme.
J. Cell Sci., 109, 409-418

Hozak P., Jackson D.A. and Cook P.R. (1996)
Role of nuclear structure in DNA replication. In: Eukaryotic DNA Replication - Frontiers in Molecular Biology.
J.J. Blow, Ed., Oxford University Press, Oxford, Chapter 5, 124-142

Kanka J., Hozak P., Heyman Y., Chesne P., Renard J.-P. and Flechon J.E. (1996) Transcriptional activity and nucleolar ultrastructure of embryonic rabbit nuclei after transplantation to enucleated oocytes.
Mol. Reprod. Dev., 43, 135-144

Hughes T.A., Pombo A., McManus J., Hozak P., Jackson D.A. and Cook P.R. (1995)
On the structure of replication and transcription factories.
J. Cell Sci., Supp. 19, 59-65

Hozak P. (1995)
Catching RNA polymerase I in flagranti: rRNA is transcribed in the dense fibrillar component of the nucleolus.
Exp. Cell Res., 216, 285-289

Hozak P., Sasseville A. M.-J., Raymond Y. and Cook P.R. (1995)
Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells.
J. Cell Sci., 108, 635-644


Hozak P., Jackson D.A. and Cook P.R. (1994)
Replication factories and nuclear bodies: the ultrastructural characterization of replication sites during the cell cycle.
J. Cell Sci., 107, 2191-2202.

Hozak P. and Cook P.R. (1994)
Replication factories.
Trends Cell Biol., 4, 48-51.

Hozak P., Cook P.R., Schoefer Ch., Mosgoeller W. an and Wachtler F. (1994)
Site of transcription of ribosomal RNA and intranucleolar structure in HeLa cells.
J. Cell Sci., 107, 639-648

Wachtler F., Mosgeoller W., Schoefer C., Sylvester J., Hozak P., Derenzini M. and Stahl A. (1993)
Ribosomal genes and nucleolar morphology.
Chromosomes Today, 11, 63-77

Hozak P., Schoefer C., Sylvester J. and Wachtler F. (1993)
Study on DNA distribution in nucleoli: Isolation of DNA from fibrillar components and ultrastructural localization of different DNA probes.
J. Cell Sci., 104, 1199-1205


Hozak P., Hassan A.B., Jackson D.A. and Cook P.R. (1993)
Visualisation of replication factories attached to a nucleoskeleton.
Cell, 73, 361-374

Cook P.R., Dolle A., Hassan A.B. Hozak P., Jackson D.A. (1993)
The role of the nucleoskeleton in RNA metabolism.
Nucleic Acids and molecular biologyl, 7, 226-237

Behalova B., Hozak P., Blahova M. and Sillinger V. (1992)
Effect of nitrogen limitation and sporulation on sterol and lipid formation in Saccharomyces cerevisiae.
Folia Microbiol., 37, 442-449


Hozak P., Geraud G. and Hernandez-Verdun D. (1992)
Revealing nucleolar architecture by low ionic strength treatment.
Exp. Cell Res., 203, 128-133


Hozak P., Roussel P. and Hernandez-Verdun D. (1992)
Procedures for specific detection of silver stained nucleolar proteins on Western blots.
J. Histoch. Cytoch., 40, 1089-1096

Hozak P., Zatsepina O.V. and Likovsky Z. (1990)
Nucleolar changes in hypotonic treatment and the possibility of isolation of nucleolar fibrillar complexes.
Nuclear Structure and function, Harris J.R. and Zbarsky I.B. Eds, Plenum Press, new York, 197-202

Hozak P., Zatsepina O.V. and Likovsky Z. (1990)
In situ separation of nucleolar components by hypotonic treatment of cells.
Biol. Cell, 68, 167-170

Hozak P., Novak J., Smetana K. (1989)
Three-dimensional reconstructions of nucleous organizing regions in PHA - stimulated human lymphocytes.
Biol. Cell, 66, 225-233

Zatsepina O., Hozak P., Babadjanyan D., Chensov I. (1988)
Morphometric study of nucleolus-organizing regions of chromosomes from swine embryo kidney cells during Go-, G2-period and mitosis.
Mol Biol., 22, 1015-1025

Zatsepina O.V., Hozak P., Babadjanyan D. and Chensov Yu.S. (1988)
Quantitative ultrastructural study of nucleous-organizing regions at some stages of the cell cycle (Go period, G2 period, mitosis).
BIol. Cell., 62, 211-218

Hozak P., Zatsepina O.V., Vasilyeva I. and Chensov Yu.S. (1986)
An electron microscopic study of nucleous-organizing regions at some stages of the cell cycle (Go period, G2 period, mitosis).
BIol. Cell., 57, 197-206

Hozak P., Zatsepina O.V. and Chensov Yu.S. (1983)
Ultrastructure, shape and number of fibrillar centers in PK-cells begin Go.
Citologia, 25, 1236-1242